durabolin injection side effects
Round, flat on both sides, beige or white with a beveled edge tablets. On one side of the pill Risk on both sides risks engraved “C 61”, on the other side of firm tablets engraved mark.
1 tablet contains active substance durabolin injection side effects digidrohlorida- monohydrate 25 mg (calculated as anhydrous substance durabolin injection side effects dihydrochloride) Excipients:lactose, corn starch, colloidal silicon dioxide (Aerosil 200), magnesium stearate.
durabolin injection side effects selectively blocking muscarinic receptors decreases the formation of gastric juice in the stomach the pH increases. At therapeutic doses, the drug does not penetrate the blood-brain barrier.
durabolin injection side effects not fully absorbed from the gastrointestinal tract. The maximum plasma concentration observed after 2-3 hours after ingestion. Mean absolute oral bioavailability of only 10-20%.
Receiving durabolin injection side effects simultaneously with food reduces the area under the concentration-time curve at 30%. durabolin injection side effects only slightly bound to plasma proteins (about 12%).
durabolin injection side effects almost does not penetrate the blood-brain and placental barriers, and in the milk of lactating women found only a minimal amount of drug.
When administered orally durabolin injection side effects appears mainly in the faeces, mainly in unchanged form . Total plasma clearance is about 250 ml / min. Renal clearance is approximately half this value, which corresponds to the glomerular filtration rate.
durabolin injection side effects excreted from the body with a mean half-life of 10-12 hours. In pharmacokinetics durabolin injection side effects did not significantly affect either hepatic or renal insufficiency.
The volume of distribution of the basic substance is about 14 liters, which corresponds approximately to the volume of the human extracellular space.
Acute gastric and duodenal ulcers; gastric ulcer and duodenal ulcer.
Dosing and Administration
The tablets should be taken about half an hour before meals with a small amount of liquid.
If your doctor is not indicated differently, the drug should be 50-150 mg / day, divided into several stages.
The usual dose regimen: 50 mg twice daily , morning and night.
Sometimes, in the first 2-3 days of treatment may be needed additional doses of the drug in the middle of the day.
Despite the rapid subjective improvement, the patient should not reduce the dose or stop taking the drug unless it is recommended by your doctor.
treatment you should be continued for 4-6 weeks.
Hypersensitivity to any component of the drug, paralytic ileus in the patient.
The maximum recommended daily dose contains 833.64 mg lactose. Patients with existing galactose intolerance (galactosemia, lactase deficiency or malabsorption of glucose-galactose in the intestine) should not use this drug.
Gastrotsepin should be used with caution in patients with glaucoma, benign prostatic hyperplasia, tachycardia.
After treatment were observed following side effects: dry mouth, accommodation disturbances, tachycardia, constipation, diarrhea, urinary retention, headache. Reported cases of allergic reactions and anaphylactic shock.
Patients with glaucoma is recommended to periodically measure the intraocular pressure.
Effects on ability to drive vehicles or machinery maintenance and mechanisms
Because of visual impairment and accommodation may develop impaired ability to drive and use machinery.
Interaction with other medicinal products
Co-administration gastrotsepin and blockers of H 2 histamine receptors is accompanied by a more pronounced reduction in the secretion of hydrochloric acid in the stomach. Gastrotsepin used in combination with anti-inflammatory drugs, did not reduce their anti-inflammatory effect and improves portability.
Pregnancy and lactation
The drug should be used in pregnant and lactating women only if the expected benefits outweigh any possible risk to the fetus or newborn.
Overdose Symptoms To date, no data on overdose in humans. However, the application of large doses of durabolin injection side effects into the possible development of the following anticholinergic effects, “tides”, dryness, and flushing of the skin; dry mouth; mydriasis; rave; tachycardia; bowel obstruction; urinary retention; jerking of muscles; chorea, athetosis. Treatment Experience durabolin injection side effects treatment of overdose is limited. In cases of poisoning with high doses of the drug, taken by mouth, treatment begins with general measures (for example, the appointment of activated charcoal, gastric lavage). Hemodialysis, blood transfusion, peritoneal dialysis and re-appointment of activated carbon does not contribute to the removal of durabolin injection side effects from the body. In cases of severe intoxication (with fever, delirium or severe tachycardia) may be appointed physostigmine in a small dose intravenously. In the case of an acute attack of glaucoma should be used preparations, which have m-nicotinic effects (pilocarpine eye drops) and immediately consult a specialist. shop steroids bm pharmaceuticals steroidwithdrawal.biz